Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

Katherine Heminger; Michael Markey; Meldrick Mpagi; Steven J. Berberich

doi:doi:10.18632/aging.100008

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Research Paper Volume 1, Issue 1 pp 89—108

Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

Figure 4. GeneChip expression of 13 known p53-regulated genes that were induced by knockdown of either siHdmX or siHdm2. Y-axis represents the average fold change (log₂) for each of the genes in the indicated siRNA transfections relative to siCon (X-axis, conditions labeled at the top of the chart).