Research Paper Volume 1, Issue 1 pp 131—145
Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density
Figure 3. Increase of mitochondrial transcript abundance in tor1Δ strains. Northern analysis of the mtDNA-encoded mRNA transcripts COX1-COX3 from wild-type (wt) and tor1Δ strains is shown, along with ethidium bromide-stained nuclear 25S rRNA as a loading control. Graphed on the right is the mean fold difference in COX1, COX2, and COX3 abundance normalized to 25S rRNA +/- one standard deviation (* designates a p-value <0.05 and ** designates a p-value <0.01 based on a student's t-test).