Review Volume 1, Issue 9 pp 762—770
Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate
Figure 2. Different ways by which FFLs can account for the enhanced phenotypic effect of miRNAs on cell fate. (A) miRNAs and TFs in FFLs tend to mutually target genes from the same pathway. (B) Additionally, co-regulated miRNAs and miRNA families co-target many genes in the same pathway, thus resulting in a significant total output, having a major effect on cell fate.