Research Paper Volume 1, Issue 11 pp 937—948

Figure 1. Lifespan of per⁰¹and CS^pD. melanogaster in normoxia and following 24h hyperoxia at different ages (marked by arrow in B-D). (A) In normoxia, there was no significant difference in mean survival curves (p=0.23) (B) Hyperoxia on day 5 did not significantly affect longevity or survival curves (p=0.12) (C) Hyperoxia on day 20 resulted in a significant reduction (p<0.05) in average survival of per⁰¹flies compared to CS^p with significant (p<0.0001) difference in survival curves. (D) Hyperoxia on day 35 resulted in more significant reduction (p<0.001) in average lifespan in per⁰¹flies compared to CS^p and significant difference in survival curves (p<0.0001). Males with rescued per function (per⁰¹{per⁺}) treated with hyperoxia on day 35 had average lifespan similar to CS^p but significantly different (p<0.001) from per⁰¹mutants.