Figure 3. Vertical mobility deteriorates faster in per01flies, as demonstrated by the RING assay. Bars represent mean height climbed (with SEM) in CSp (open bars) and per01(black bars) males at indicated age. The climbing performance of per01males on day 5 was significantly higher (p<0.001) compared to CSp. With age, a rapid deterioration in climbing performance was noted in per01flies with mobility being significantly lower (* p<0.001) on day 20, 35, and 50 compared to age-matched CSp controls.