Research Perspective Volume 1, Issue 11 pp 957—960

Surviving in the cold: yeast mutants with extended hibernating lifespan are oxidant sensitive

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Figure 1. Oxidant-resistance is not a premise for long-time survival in the cold. (A) 106 48-position agar plates containing a systematic yeast knock-out collection were incubated at 4°C and replicated after 12 and 58 months, respectively. (B) GO analysis of surviving strains; the majority groups to metabolic processes (C) Comprehensive phenotypic analysis of mutants that survived for 58 months in the cold. Resistance to oxidants or reductants is the exception.