← Back
Research Paper Volume 1, Issue 12 pp 1008—1016

Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential

class="figure-viewer-img"

Figure 3. Cellular hypertrophy during senescence induction. HT-p21 cells were grown in 60 mm wells and cell numbers, soluble protein and GFP were measured daily. Closed bars: HT-p21 cells were treated with IPTG (+IPTG). Open bars: Untreated HT-p21 cells (-IPTG). Protein per cell and GFP per cell were constant in proliferating (-IPTG) cells. Protein per cell and GFP per cell increased exponentially in non-proliferating (+IPTG) cells.