Research Paper Volume 2, Issue 12 pp 981—989
CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits
Figure 5. CD36 stimulation improves visual function in ApoE−/−. Representative rod-cone (0.6 log.cd.sec.m−2) and rod (−2.7 log.cd.sec.m−2) electroretinographic tracings from WT and ApoE−/− under HFHC treated with NaCl or EP80317 (A). Amplitudes of the a-waves (rod-cone ERG) (B) and b-waves (rod and rod-cone ERGs) (C) were significantly reduced in ApoE−/− mice injected with NaCl (grey bars) compared to WT mice (white bars); EP80317 treatment significantly attenuated this decrease (black bars). Values are mean ± SEM; n=6/group. *p<0.05 compared to values without asterisks.