Research Paper Volume 2, Issue 11 pp 785—790

CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells

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Figure 3. Human CENP-A mRNA expression is indepen-dent of donor age in islet and exocrine cells. Isolated endocrine and exocrine cells were analyzed for CENP-A mRNA levels with quantitative RT-PCR and normalized to 18S mRNA (donors of 18-58 years of age, N=13).