Research Paper Volume 2, Issue 12 pp 936—944

Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice


Figure 2. Effect of CLOCK on mouse lifespan. Kaplan-Meyer survival curves of wild type and Clock−/− mice of both genders. (a) Survival data for death only from natural causes, (b) combined data for mice which died from natural causes and mice sacrificed due to severe dermatitis. For both graphs, the genotypes differ significantly (p<0.01).