Research Paper Volume 2, Issue 12 pp 936—944

Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice


Figure 4. Deficiency of CLOCK results in increased rate of cataract development. Chronological incidence of cataracts in wild type and Clock−/− mice. Abscissas show the mouse ages at which data for each time point were collected. Ordinates show the fraction of eyes with cataracts. (a) Males, (b) females. For both graphs, the genotypes differ significantly (p<0.01).