Research Paper Volume 4, Issue 6 pp 402—416

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice

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Figure 5. Blood pressure in WT, mIGF-1 Tg and mIGF-1 Tg; SIRT1 CKO mice.

Noninvasive blood pressure values in conscious mice were measured using the tail-cuff method. (A) Diastolic blood pressure (DBP); (B) Systolic blood pressure (SBP). Results are means ± SE of 3-8 animals for each genotype (*p versus WT mice). NS= not significant.