Research Paper Volume 4, Issue 9 pp 590—605

Figure 2. Receiver-Operating Characteristic (ROC) curve analysis of differentiation between MCI patients and age-matched controls obtained with different biomarker pairs.

The areas under the ROC curve (AUC) are reported. Sensitivity, specificity and accuracy for each biomarker/normalizer pair are calculated for the “cutoff” point (indicated as a dot on each plot); the cutoff point is the ratio of paired miRNA, at which a sample is equally likely to belong to the AMC and the MCI groups (see Supplementary materials for more details).