Research Paper Volume 4, Issue 9 pp 590—605

Plasma microRNA biomarkers for detection of mild cognitive impairment

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Figure 4. Comparison of miRNA biomarker pairs in plasma of Group 1 (30-50 years old, “CY”) and Group 2 (70-80 years old, “AMC”) individuals with normal cognitive functions.

The concentrations of miRNA in plasma samples of Group1 (30-50 years old, CY) and Group2 (70-80 years old, AMC) donors with normal cognitive function, 20 samples in each group, were measured by RT-PCR and the ratio of various miRNA was calculated as 2−ΔCt × 100. See the legend to Fig. 1 for the description of the statistical analysis.