Research Paper Volume 4, Issue 9 pp 620—635
RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice
Figure 4. RhTFAM treatment increases expression of brain mitochondrial RNA polymerase (POLRMT).
(top) expression of POL-g and POLRMT in brains of young (5 month, n=6) and old (21 month, n=9) mice. There were no significant differences. (bottom) effects of rhTFAM on expression of POL-g and POLRMT in brains of old (21 month) mice (n=9 each group). RhTFAM treatment increased expression of POLRMT (p=0.0045 by paired t-test).