Research Paper Volume 4, Issue 9 pp 620—635

RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice

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Figure 5. Effects of aging and rhTFAM treatment of aged mice on expression of brain Sirt3.

In (A), expression of Sirt3 in young (n=6) compared to old (n=90 brains was significant at p<0.0001 by unpaired t-test. In (B), rhTFAM treatment (n=9) significantly increased Sirt3 expression compared to CTL treatment (n=9) in aged mice at p=0.0012 by unpaired t-test.