Research Paper Volume 4, Issue 9 pp 636—647
Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging
Figure 2.
Life span of wild type and mutant C. elegans animals. (A) Survival curves of wild type (N2) and wrn-1(gk99) animals grown at 25°C. (B) Survival curves of wild type (N2) and mir-124 (n4255) strains grown at 25°C. (C) Survival curves of wild type (N2) and wrn-1;mir-124 double mutant animals grown at 25°C. All experiments were performed with five different pools of 20 to 30 animals of each genotype. The indicated P-values were obtained using the log-rank test method.