Research Paper Volume 4, Issue 10 pp 715—722
New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis
Figure 2.
Rapatar increases lifespan in p53−/− mice. Mice received Rapatar at 0.5 mg/kg via gavage according to the schedule described in Materials and Methods. Rapatar increased lifespan from 23 to 31 weeks (p<0.001, Mantel-Cox log-rank test).