Research Paper Volume 4, Issue 10 pp 715—722
New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis
Figure 4.
Rapatar delays development of sarcomas in p53−/− mice. (A) Liver sarcoma in 172-old control mouse. (B,C) Sarcoma developed in 261 day- and 204 day-old Rapatar-treated mice. No metastases are detected. D. Sarcoma in 212-day old Rapatar-treated mouse with metastases in the lung.