Research Paper Volume 4, Issue 10 pp 695—708

Figure 6. SASP factor abundance as a function of NF90 levels.

(A) The levels of the SASP factors shown (GM-CSF, MCP-1, GROa, IL-6, and IL-8) were measured in supernatants from cultures of WI-38 cells (P, pdl 20; S, pdl 54) and IDH4 cells (+Dex, -Dex for 9 days). (B) The levels of the SASP factors were measured in supernatants from cultures of WI-38 cells (pdl 30) and IDH4 cells (+Dex) that were transfected with Ctrl siRNA or NF90 siRNA. SASP factor levels were studied 1–3 weeks after transfection of WI-38 cells (top) and 1 and 2 week after transfection of IDH4 cells (bottom). In (A,B), data represent the means +SD from 3 independent experiments.