Review Volume 4, Issue 12 pp 861—877

Answering the ultimate question “What is the Proximal Cause of Aging?”

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Figure 3. The relationship between the onset of age-related disease (ADR) and it frequency.

The onset of the ADR determines its frequency and the precision of the onset. Arrows: Age of age-related diseases and its frequency in general population. Small circles: Genertic variants of the similar disease, which is a rare case in general population. High frequency is only (!) in very small groups of genetically-abnormal patients.