B cell responses to the 2011/12-influenza vaccine in the aged

Raj K. Kurupati; Senthil Kannan; Xiang; Zhi Xiang; Susan Doyle; Sarah Ratcliffe; Kenneth E. Schmader; Hildegund CJ Ertl

doi:doi:http://dx.doi.org/10.18632/aging.100541

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Research Paper Volume 5, Issue 3 pp 209—226

B cell responses to the 2011/12-influenza vaccine in the aged

Figure 4. Circulating B cells.

4a shows numbers of naïve B cells per 10⁶ CD3⁻CD14⁻ live PBMCs. Naïve B cells (NBCs) were identified by gating on CD19⁺CD20⁺CD27⁺CD38⁻IgD⁺ cells. (a) shows data for PBMCs from individual aged subjects, (b) shows means of the same set of data, (c) shows data for PBMCs from individual younger subjects, (d) shows means for the same data. 4b shows numbers of memory B cells per 10⁶ CD3⁻CD14⁻ live PBMCs. Memory B cells were identified by gating on CD19⁺CD20⁺CD27⁺CD38⁻IgD⁻ cells. The graphs are arranged as in 4A.