Research Perspective Volume 5, Issue 3 pp 144—150

The sirtuins, oxidative stress and aging: an emerging link

class="figure-viewer-img"

Figure 3. Aging and Mitohormesis.

Theoretical curve showing how low doses of a stressor may have beneficial effects by activating intracellular stress response pathways. If the stressor exceeds the capacity of the stress response system to maintain homeostasis, then deleterious phenotypes are observed.