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Research Paper Volume 5, Issue 4 pp 276—287

Autophagy drives epidermal deterioration in a Drosophila model of tissue aging

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Figure 6. Autophagy is Required for Epidermal Aging.

(A-B) Anti-Fasciclin III immunofluorescence (green) of Atg7d77 epidermal whole mounts (n ≥ 10). Bar, 20 μm. A, 1 d. B, 14 d. (C) Quantification of Atg7d77 epidermal deterioration with age. Asterisks, significant comparisons by Chi square test (p < 0.05). n. s., not significant. (D) Quantitative comparison of epidermal deterioration in Atg7d77 mutants, NP2108-GAL4/Atg7-IR flies and w1118 controls. Significance indicators as in C.