Research Paper Volume 5, Issue 5 pp 347—356

FOXO1 regulates expression of a microRNA cluster on X chromosome

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Figure 4.

Inhibition of phosphoinositol-3-kinase elevates the expression of miRNA-506. LNCaP (prostate carcinoma) or MCF7 (breast carcinoma) cells were treated for 24 hours with PI3K inhibitor LY294002. The levels of miR-506 were measured using quantitative PCR with RNU6B as an internal standard, and normalized to those in untreated controls.