Research Paper Volume 5, Issue 6 pp 394—411

Age-related micro-RNA abundance in individual C. elegans

class="figure-viewer-img"

Figure 1. Dynamic changes of miRNAs with age.

(A) Survivorship of a population of N2 (wild type) animals, from which individuals were harvested for analysis at Day 1 and Day 12 of adulthood. (B-G) Normalized Ct values describing miRNA abundance in individual worms (each point represents data from a single animal) at two ages are shown for mir-44 (B), mir-51 (C), mir-240 (D), mir-58 (E), mir-60 (F), and mir-235 (G). (H) Graphical representation of the fold change in miRNA abundance between young and old animals. In all graphs with error bars they indicate the standard error of the mean. In individual worm graphs each point is the average from 2-3 technical replicates.