Research Paper Volume 5, Issue 6 pp 474—484

Rapamycin suppresses brain aging in senescence-accelerated OXYS rats

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Figure 3.

Effect of rapamycin (0.5 mg/kg per day) on Tau, Tau phospho T181 and APP in the hippocampus of OXYS and Wistar rats (n=6). A: Levels of App by immunoblot. B: Levels of total Tau. C: Levels of Tau phospho T181. D: Representative immunoblots of App, Tau and Tau phosphor T181 in the hippocampus of OXYS and Wistar rat. * -P < 0.05, statistically significant effect of rapamycin; #−P < 0.05 between OXYS and Wistar rats. Data are presented as mean ± SEM.