Research Paper Volume 5, Issue 9 pp 643—652

Figure 1. Aged CD137^−/− and CD137L^−/− mice have reduced myelopoiesis in bone marrow compared to WT.

Bone marrow cells of 3 and 12 months old WT, CD137^−/− and CD137L^−/− mice were stained for CD11b, Ly6G and Ly6C. (A) Gating strategy for (B) granulocytes (CD11b⁺, Ly6C⁺, Ly6G⁺) and (C) monocytes (CD11b⁺, Ly6C⁺, Ly6G⁻) in the bone marrow. (B) Number of granulocytes and monocytes in the bone marrow. Each group consisted of at least 5 mice. Data are representative of two independent experiments. *p<0.05.