Research Paper Volume 5, Issue 9 pp 643—652

Figure 2. Increased numbers of CD4⁺ T cells in aged mice.

Bone marrow cells from 3 and 12 months old WT, CD137^−/− and CD137L^−/− mice were stained for CD3, CD137, CD4 and CD8. (A) Gating strategy of CD137⁺ T cells. (B,C) Numbers of (B) CD137⁺, CD4⁺ and (C) CD137⁺, CD8⁺ T cells. (D,E) Numbers of (D) CD137⁻, CD4⁺ and of CD137⁻, CD8⁺ T cells. Each group consisted of at least 5 mice. Data are representative of two independent experiments. *p<0.05.