Research Paper Volume 5, Issue 9 pp 692—703
Age-associated miRNA Alterations in Skeletal Muscle from Rhesus Monkeys reversed by caloric restriction
Figure 4. Identification of novel miRNAs in young and old skeletal muscle tissues from rhesus monkeys.
(A) Venn diagrams showing the number of miRNAs identified in young (Y) tissues (left), old (O) tissues (middle) and shared between young (Y) and old (O) tissues (right). (B)Partial list of novel miRNAs, 1location of the miRNA precursor in the human genome, 2miRDeep2 score represents the log-odds probability of a sequence being genuine miRNA precursor versus the probability that it is a background hairpin, 3mature miRNA sequence used for validation, 4estimated probability that a predicted novel miRNA with a score of this or higher is a true positive, 5sum of read counts that map to the predicted mature, loop and star miRNAs, and 6similar miRNA sequences found in human genome match the novel sequences detected in rhesus monkey.