Figure 5. Predicted targets and pathways for the indicated age-associated miRNAs.
Predicted targets for the 3 miRNAs were obtained using TargetScan software and the overlapping targets were visualized using a Venn diagram (A). The overlapping targets are indicated. (B) The predicted targets from TargetScan for each miRNA were used for Ingenuity Pathway Analysis. The top five pathways for each parameter are listed and where applicable the number of genes (#) for the particular pathway. For each parameter listed, P<0.05. Dev.=development.