Functional metagenomic profiling of intestinal microbiome in extreme ageing
Figure 1.Centenarians and elderly differ in both microbiota composition (a) and urine metabotypes (b).
a, Principal coordinates analysis (PCoa) of Euclidean distances between HITChip profiles [8]. PC1 represents 36.46% of the variability, PC2 19.91%. b, Two centenarian subjects versus elderly group; R2 = 0.394, Q2 = 0.596, two-component model. The ellipses represent the Hotelling's T2 with 95% confidence. Subjects are colored according to the age groups: red for centenarians, blue for elderly people, green for the young adult.