Research Paper Volume 5, Issue 12 pp 902—912

Functional metagenomic profiling of intestinal microbiome in extreme ageing

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Figure 1. Centenarians and elderly differ in both microbiota composition (a) and urine metabotypes (b).

a, Principal coordinates analysis (PCoa) of Euclidean distances between HITChip profiles [8]. PC1 represents 36.46% of the variability, PC2 19.91%. b, Two centenarian subjects versus elderly group; R2 = 0.394, Q2 = 0.596, two-component model. The ellipses represent the Hotelling's T2 with 95% confidence. Subjects are colored according to the age groups: red for centenarians, blue for elderly people, green for the young adult.