Research Paper Volume 6, Issue 3 pp 207—214
Hexosamine pathway but not interstitial changes mediates glucotoxicity in pancreatic β-cells as assessed by cytosolic Ca2+ response to glucose
Figure 5.
Insulin secretory response to physiologic glucose challenge assessed by decrease of quinacrine fluorescence in β-cells following culture in high (22.3 mM) glucose (A) and control culture in 5.6 mM glucose (B). C, Rate of quiniacrine fluorescence decrease. Numbers above the bar indicate the number of recordings.