Research Paper Volume 6, Issue 3 pp 215—230
Dynamic regulation of genetic pathways and targets during aging in Caenorhabditis elegans
Figure 5. The heat map and hierarchical clustering in TGF-beta signaling pathway during aging.
(A) It showed the heat map and hierarchical clustering in TGF-beta signaling pathway from the stage of L4 to D6. The samples (column) were clustered into two groups, three replicates in the stage of L4 (L4-1, L4-2 and L4-3) were clustered together and three replicates at day 6 (D6-1, D6-2 and D6-3) were clustered together. There were 30 involved genes (row) in TGF-beta signaling pathway from L4 to D6, which were mainly clustered into 3 groups (the group from A to C). (B) It showed the heat map and hierarchical clustering in TGF-beta signaling pathway from the stage of D6 to D15. The samples were clustered into two groups, three replicates at day 6 (D6-1, D6-2 and D6-3) were clustered together and three replicates at day 15 (D15-1, D15-2 and D15-3) were clustered together. There were also 30 involved genes in TGF-beta signaling pathway from D6 to D15, which were mainly clustered into 2 groups (the group of A and B).Red is for up-regulated and green is for down-regulated.