Research Paper Volume 6, Issue 4 pp 281—295

Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease

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Figure 1. CD36 expression is positively associated with age in liver biopsies from patients with normal livers, but not in liver biopsies from patients with non-alcoholic steatosis (NAS).

(A) CD36 immunostaining of liver biopsy tissue from: young normal liver, 29 years old (Left upper panel), old normal liver, 76 years old (Right upper panel), young non-alcoholic steatosis (NAS), 31 years old (Left lower panel), old NAS, 75 years old (Right lower panel). Original magnification for all microphotographs: 400x. Each microphotograph includes a 2x zoom detail. (B) Hepatic CD36 expression index in liver biopsies from patients with normal livers and NAS. (C) Correlation between age and hepatic CD36 expression index in normal livers and NAS.