Research Paper Volume 6, Issue 4 pp 296—310

Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians

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Figure 1. Mitochondrial mass increases in DFs from LLI.

(A) Citrate synthase activity expressed as nmol/min/mg of total cellular protein; (B) protein content expressed as μg protein/106 cells ratio; (C) citrate synthase activity expressed as nmol/min/106 cells; *p<0.05 LLI vs Old and **p<0.01 LLI vs Young. Data are presented as the mean value ± SD. Two independent experiments were performed on DFs of each donor.