Research Paper Volume 6, Issue 4 pp 311—319
Cardiac BNP gene delivery prolongs survival in aged spontaneously hypertensive rats with overt hypertensive heart disease
Figure 1.
AAV9 vector facilitates long-term cardiac gene delivery in spontaneously hypertensive rats (SHR). Distribution of luciferase activities in SHR organs was monitored by Xenogen IVIS Living Image 18 months after systemic adeno-associated virus (AAV) vector administration. Strong luciferase expression in heart demonstrated efficient long-term cardiac gene delivery by AAV9 vector in SHR.