Research Paper Volume 6, Issue 7 pp 545—563
A role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblasts
Figure 7. Chaetocin is more cytotoxic and induces senescence in low PD cultures.
(A) Cell viability after treatment with different concentrations (5 nM, 10 nM, 25 nM, 50 nM, 75 nM, 100 nM, or 200 nM) of chaetocin as determined by the MTT assay. Averages of measurements from three different cultures ± SD. (B) SA-β-GAL staining of PD 47 cultures treated with 0 nM, 5 nM, 10 nM, and 25 nM of chaetocin. Pictures were taken at 10× magnification.