Research Paper Volume 6, Issue 7 pp 564—574
WI-38 senescence is associated with global and site-specific hypomethylation
Figure 1. Reduced protein levels of DNMT1 correlate with decreased global DNA methylation.
(A) DNMT1 and MAT2A protein levels normalized to protein levels in PD 38 cells. Averages of three biological replicates ± standard deviation. (B) Western blot images. (C) Cytosine extension assay showing average incorporation of radioactively labeled dCTP from three samples per PD level; error bars indicate standard.