Research Paper Volume 6, Issue 8 pp 645—660
SIN3 is critical for stress resistance and modulates adult lifespan
Figure 4. Ubiquitous Sin3A knockdown (KD) causes decreased survival.
Mean survival of control (-RU486), SIN3 KD or GFP RNAi (+RU486) flies is indicated. A and B. SIN3 KD I (p<0.0001 using the logrank (Mantel-Cox) test), C and D. SIN3 KD II (p<0.0001), E and F. GFP RNAi serves as an additional control.