Research Paper Volume 6, Issue 8 pp 690—704
hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling
Figure 3. hNAG-1 transgenic mice have increased metabolism.
(a), Heat production (W/kg) in female hNAG-1 and Wt mice as determined indirect colorimeter (n=5). (b-c), Consumption of O2 and VO2 (ml/h/kg) in female hNAG-1 and Wt mice during day and night time (n=5). (d), Respiratory quotient (RER) as calculated from VO2 and VCO2 in 1398 hNAG-1 female mice. Data are presented as mean ± SE. a, p<0.05, b, p<0.01 and c, p<0.001 as determined by Student's t-test.