Research Paper Volume 6, Issue 8 pp 690—704
hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling
Figure 5. hNAG-1 transgenic mice have reduced IGF-1/Insulin/mTOR signaling.
Phosphorylation of proteins of IGF-1/insulin/mTOR signaling pathway was analyzed by Western blot (n=3) in abdominal WAT. Both samples from 30 wk and 95 wk old animals were analyzed.