Research Paper Volume 6, Issue 9 pp 742—754
Rapamycin-induced metabolic defects are reversible in both lean and obese mice
Figure 1.
(A) Glucose tolerance tests for C57BL/6 males fed indicated diets for 2 months. (B) Area under curve (AUC) calculations for glucose tolerance tests following 2 or 4 months feeding indicated diets. (C) Insulin tolerance tests for C57BL/6 males fed indicated diets for 2 months. (D) AUC for insulin tolerance tests for insulin tolerance tests following 2 or 4 months feeding indicated diets. For all, symbols represent average (± SEM) values for n=6 mice at indicated time point for mice fed low fat (circle) or high fat (triangle) diets with (solid) or without (open) encapsulated rapamycin (eRAPA). F and p values are given for 3 way ANOVA testing indicated variables.