Functional properties of bone marrow derived multipotent mesenchymal stromal cells are altered in heart failure patients, and could be corrected by adjustment of expansion strategies

Renata I. Dmitrieva; Alla V. Revittser; Maria A. Klukina; Yuri V. Sviryaev; Ludmila S. Korostovtseva; Anna A. Kostareva; Andrey Yu. Zaritskey; Evgeny V. Shlyakhto

doi:doi:http://dx.doi.org/10.18632/aging.100716

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Research Paper Volume 7, Issue 1 pp 14—25

Functional properties of bone marrow derived multipotent mesenchymal stromal cells are altered in heart failure patients, and could be corrected by adjustment of expansion strategies

Figure 1. Representative results of routine analysis of BM-MMSC samples quality.

(A) Immunophenotype; Performed on Guava EasyCyte 8 using ExpressPro software. (B,C) Ability to differentiate: (B) Adipogenic differentiation (x200, OilRedO staining) and (C) osteogenic differentiation (x200, Alizarin staining).