Research Paper Volume 7, Issue 8 pp 568—578

Stochastic epigenetic mutations (DNA methylation) increase exponentially in human aging and correlate with X chromosome inactivation skewing in females

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Figure 2. Schematic description of the SEM.

For each probe, a Box-and-whiskers plot analysis identifies extreme outliers samples. For each sample epimutations are detected, counted and mapped considering their genomic position.