Research Paper Volume 7, Issue 10 pp 776—787

Proteasome function is not impaired in healthy aging of the lung

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Figure 4. Aged LMP2 knockout mice show senile emphysema in the lung.

(A) Representative H&E staining of lungs from young and aged LMP2−/− mice. Images from two individual animals are depicted per group (B) Western blot analysis of proteasome subunit expression in LMP2−/− mice and (C) quantification of protein expression relative to the β − actin loading control. Bar graphs show mean+SEM.