Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (<i>Callithrix jacchus</i>)

Corinna Ross; Adam Salmon; Randy Strong; Elizabeth Fernandez; Marty Javors; Arlan Richardson; Suzette Tardif

doi:doi:http://dx.doi.org/10.18632/aging.100843

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Research Paper Volume 7, Issue 11 pp 964—973

Metabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)

Figure 6. Immunoblot results.

Immunoblot results for the following: adipose triglyceride lipase (ATGL), pyruvate carboxylase (PCB), glucose-6-phosphatase α (G6Pase), glucose-6-phosphate isomerase (GPI), peroxisome proliferator-activated receptor γ (PPARγ), phospho-pyruvate dehydrogenase kinase (p-PDK1), pyruvate dehydrogenase kinase (PDK1), phosphoenol-pyruvate carboxykinase 1 (PCK1), sterol regulatory element-binding protein 1 (SREBP1) corrected by actin. A. Adipose tissue collected at sacrifice following 14 months of rapamycin (black) or control dosing (grey) (mean ± SE) B. Liver tissue collected at sacrifice following 14 months of rapamycin (black) or control dosing (grey) (mean ± SE) *indicates significance p<0.05.