Research Paper Volume 7, Issue 12 pp 1212—1222

Survival of irradiated recipient mice after transplantation of bone marrow from young, old and “early aging” mice

class="figure-viewer-img"

Figure 1. Long-term survival of C57Bl/6 recipients.

(A) Four-week old female C57Bl/6 mice were lethally irradiated and transplanted with 2 × 106 BMCs from 8-week old +/m or wild-type donors (n=20/group). (B) Four-week old female C57Bl/6 mice were lethally irradiated and transplanted with 2 × 106 BMCs from 18-week old +/m (n=13) or wild-type donors (n=17). No differences were detected between the two groups of recipients suggesting that lifespan was not reduced by transplantation of +/m BMCs.