Research Paper Volume 8, Issue 6 pp 1201—1215

Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

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Figure 7. Metabolic dysfunction in AdicerKO mice under nutrient restriction. Schematic model of the metabolic consequences of fat-specific Dicer knockout in mice under nutrient restriction. FA, fatty acid. BCAA, branched-chain amino acid. SCAC, short-chain acylcarnitines. IR, insulin receptor. Solid arrows, activation. Dashed arrows, transport. T-bars, inhibition.