Research Paper Volume 8, Issue 6 pp 1236—1248

Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma

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Figure 2. HDAC4 silencing inhibits cell proliferation. Real-time qRT-PCR analysis of HDAC4 mRNA expression in (A) KYSE30 and (B) EC/CUHK1 cell lines transfected with HDAC4 specific siRNAs or a control siRNA. CCK8 assay was then performed to evaluate cell growth of (C) KYSE30 and (D) EC/CUHK1 cells). Each value represents the mean ± http://S.D.in three independent experiments. * P<0.05; ** P< 0.01. OD, optical density.